% replaces any number of letters (la% - lake, lamp)_ replaces one letter (ca_ - car, cat)
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The Crossword Solver found 209 answers for The New York Times crossword clue ___ Major 4 letters. The answers have between 3 and 11 letters.

AnswerClue
BLOWmajor setback
OPUSmajor work of art
URSA___ Major (the Big Dipper)
IPOSmajor N.Y.S.E. events
ECONwharton major, in brief
LPGAthe Evian Championship is one of its majors: Abbr.
MAINmajor water source
MAJORundergraduate’s declaration
MAJOR*Salpha and Beta Ursae ___ (pointers to 68-Across)
MEGAMERGERunion of two major companies
HEGELphilosopher who was a major influence on Marx
APLITh.S. course for future English majors
ASTEROIDwhat had a major impact on this puzzle’s theme?
TAROTdeck with the Major and Minor Arcana
ALCOAmajor metals manufacturer
TRIALmajor ordeal
POWERBROKERbefore midnight: One with major influence
MCATSexams for some science majors
PEKOEvariety #2, a major export of Sri Lanka
PHENOMSminors who look to be headed to the majors
GOLDGLOVEmajor-league award for fielding prowess
COLLEGEmajor undertaking?
MCATShurdles for some bio majors
CANALmajor street in New York City or New Orleans
LEXmajor Manhattan thoroughfare, informally
NBColdest major TV network in the U.S.
WHEATmajor export of Ukraine
RIFTSmajor faults
DRSa majority of the characters on TV’s “St. Elsewhere,” in brief
COMETepiphany that precedes a major change
AORTAmajor artery
OPERAfield for a voice major, perhaps
YAHOO!*Major fantasy sports platform
SUNNIlike the majority of Egyptians
SNEAKERmajor product of Jordan
MOYERjamie who pitched on eight major-league teams over his 25-year career
ARENAstop on a major tour
SAGASmajor ordeals
SNOWDAYSpossible result of a major fall
EWEanimal whose name, when capitalized, is a major West African language
LITCRITrhyming subject for an English major
NCAATITLEmajor honor for a univ. sports team
SNOWDAYbreak after a major fall?
FAULTLINESmajor rifts
ADSmajor campaign expense
SEALYmajor mattress maker
ONEILbuck ___, first Black coach in Major League Baseball
TOBACCOmajor crop of North Carolina
DOGSTARbrightest point in Canis Major, familiarly
ALONElike Tom Hanks for the majority of “Cast Away”

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