% replaces any number of letters (la% - lake, lamp)_ replaces one letter (ca_ - car, cat)
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The Crossword Solver found 22 answers for The New York Times crossword clue first lady 3 letters. The answers have between 3 and 9 letters.

AnswerClue
EVAwith 45-Down, pre-marriage name of a 1940s-’50s first lady
EVEfirst lady?
LOU___ Hoover, first lady before Eleanor Roosevelt
EVEfirst lady
ELLAfirst name of the “First Lady of Jazz”
ELLAFirst Lady of Song,” familiarly
PARKSthe First Lady of Civil Rights
MAMIEfirst lady between Bess and Jackie
TODDmary ___, first lady’s maiden name
LAURAfirst lady Bush
ELEANORlongest-serving U.S. first lady, informally
BARBARAfirst lady before Hillary
GISHlillian ___, the First Lady of American Cinema
ELLAjenkins known as “The First Lady of Children’s Music”
TODDmaiden name of an 1860s first lady
RAISA___ Gorbachev, former Soviet first lady
ELEANORamerica’s longest-serving first lady, familiarly
ADAMfirst lady’s husband
ASTORlady ___, first female member of Parliament
LAURABUSHfirst lady of 2001 to ’09
BARABUSHformer first and second lady
SCOTLANDcountry with the first 18-Across venue (for ladies only, 1867)

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