% replaces any number of letters (la% - lake, lamp)_ replaces one letter (ca_ - car, cat)
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The Crossword Solver found 196 answers for The New York Times crossword clue responsibility 4 letters. The answers have between 3 and 14 letters.

AnswerClue
ESPfacetious response to “How’d you know that?”
AYEresponse to an order
FEEDBACKresponses
DROO/LLhave a Pavlovian response
WAY“No ___!” (or its response)
NICESAVEsarcastic response to backpedaling
IMINHEREpossible response to “Where are you?”
WORSEresponse during an eye exam
VAXshot that produces an immune response to a virus, slangily
DENADAresponse to “Gracias”
OWNtake responsibility for
OHWOWresponse to stunning news
OUIpossible response to a question that begins “Est-ce que ?”
PRESENTroll call response
BLAMEhold responsible
REACTIONGIFanimated response?
CITATIONNEEDEDresponse to not getting the reference?
TCELLsmall component of an immune response
TMIresponse to hearing all the gory details
EEKpossible response to a squeak
NOSsome survey responses
IAMresponse to “Who’s ready?”
YOUANDWHATARMYunfazed response to a threat from 20-, 31- or 38-Across?
OOFgut-punch response
YESYOU“Who, me?” response
ITSNOTFARresponse to “Are we there yet?”
YOUTOOresponse to “Have a nice day!”
FAELWENAstart behaving more responsibly, literally?
SKULLemoji that might be used in response to a funny text
WHYSHOULDIresponse akin to “Says who?!”
SAMETOYOUinapt response when somebody says “Happy birthday!,” presumably
NOLUCKSOFARpossible response to “Did you find it?”
AWWresponse to a baby animal picture
ARENTIcoy response to a compliment
DERIENresponse to “Merci”
WELOSTsad response to “How was the game?”
LIKESpositive Instagram responses
TERSElike the responses of “yes” or “no”
DENADA“Gracias!” response
OWNITtake responsibility for something
GOOSEBUMPS*Bodily response to something eerie
CRINGEresponse to an approaching embarrassment
SHINEONdeceive, especially to avoid responsibility for something
TWEETSresponsibility for a social media manager
ANTIGENimmune response trigger
GOODANSWER“Your response is what I hoped you’d say”

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