% replaces any number of letters (la% - lake, lamp)_ replaces one letter (ca_ - car, cat)
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The Crossword Solver found 35 answers for The New York Times crossword clue substance. The answers have between 3 and 10 letters.

AnswerClue
PEDillegal substance, in sports lingo
AGARSsubstances in culture dishes
DEAagcy. that carries out the Controlled Substances Act
GOOsticky substance
LYEsubstance in a bagel-making “bath”
ICENINEcrystallizing substance in Kurt Vonnegut’s “Cat’s Cradle”
EPAorg. that enforces the Toxic Substances Control Act
SOAPsubstance originally made with animal fat and wood ash
CONCRETEsecond-most-used substance in the world, after water
HEMOGLOBINsubstance that makes blood red
GOOSsticky, drippy substances
DDTsubstance banned for agricultural use in 1972, for short
LYEScaustic substances
IDEALGAStheoretical substance for which a chemistry law is named
MEATsubstance, so to speak
METH“Breaking Bad” substance
TARla Brea substance
GOOPmessy, semiliquid substance
HEFTsubstance
AGARsubstance in a petri dish
OILslick substance
PEDSbanned substances in sports, for short
ROSINsubstance used by gymnasts and cellists
MUDSmucky substances
LSDpsychedelic substance
ALKALIcorrosive substance
YLEMtheoretical primordial substance
FLUFFstuff of little substance
SNAILanimal whose teeth are the strongest substance in the natural world
HOTOILmassage therapist’s substance
TONICinvigorating substance
SOILpotter’s substance
ALOEGELsunburn-soothing substance
OXIDIZERsubstance that helps a spaceship’s fuel burn
BASALTvolcanic substance

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